This profile will test 7 hormones via LC-MS that is available for both females and males, including estradiol (E2), estrone (E1), estriol (E3), progesterone (Pg), testosterone (T), dehydroepiandrosterone sulfate (DHEAS), and cortisol (C).
The LC-MS method shines a much brighter light on the full steroid hormone cascade and provides more insight into clinical problems that might arise with insufficient or excessive hormone therapies.
ZRT Laboratory now offers a comprehensive LC-MS/MS saliva assay that measures the levels of 7 endogenous steroid hormones including estrogens, progestogens, androgens. The LC-MS/MS assay expands beyond the 5-steroid panel of parent hormones (estradiol, progesterone, testosterone, DHEAS, and cortisol) currently tested by immunoassay (IA) at ZRT Laboratory.
LC-MS has some advantages over EIA and vice versa. LC-MS is more sensitive at very low levels which can be helpful when hormones are in very low concentration. LC-MS may also offer advantages when high dose hormones are being used topically which may cause cross reactions with antibody testing.
It is also a great test to determine how different types of hormones and their administration routes (e.g., oral, topical, transdermal patch, IM/SC injections, pellet, vaginal) affect their bioavailable (saliva) levels.
The LC-MS test is also a more useful tool for understanding what pathways precursor hormone therapies (e.g., pregnenolone, DHEA, progesterone, testosterone) take to become active estrogens, progestogens, androgens.
All Tests Included:
Estrogens Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone (Pg), Testosterone (T), DHEA-S (DS), Cortisol (C).
Lab | |
---|---|
ZRT | |
Sample Type | |
Saliva | |
Estrogens (LCMS-Saliva) | |
Estradiol (E2) | |
Estriol (E3) | |
Estrone (E1) | |
Progestogens (LCMS-Saliva) | |
Progesterone (Pg) | |
Androgens (LCMS-Saliva) | |
Testosterone (T) | |
Adrenal (LCMS-Saliva) | |
Dehydroepiandrosterone sulfate (DHEA-S), (DS) | |
Glucocorticoids (LCMS-Saliva) | |
Free Cortisol (FCnx1) (C) |
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The Canary Club is an educational advisory group with a team of medical advisors headed by Richard Shames, M.D.
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